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These factors contributed to the technique needing to be more sensitive than other assays

One notable exception is the observation in significant studies that NAC is highly effective in elevating glutathione under conditions where there has been a dramatic (acute depletion) drop in intracellular glutathione levels, for instance, as is the case in acetaminophen overdose

They suggested that YKL-40 could be as a possible biomarker to identify patients at greatest risk of sustained renal failure following transplantation

A prudent approach assumes some tolerance potential and incorporates cycling to maintain effectiveness