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Professional liability considerations may differ from those associated with FDA-approved medications, and providers should maintain comprehensive documentation of treatment rationale and patient consent

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Genetic deletion of HDAC4 in skeletal muscles caused earlier onset of ALS in a mouse model, suggesting a potential risk in use of HDACi for treatment of ALS (Pigna et al., 2019)

Forms of B12 Used in Compounded Formulations Two forms of B12 appear most commonly in compounded semaglutide preparations