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doi:10.1016/S0140-6736(23)01053-X PubMed: This trial evaluated retatrutide in 281 participants with type 2 diabetes, showing up to 16.94% weight loss and significant HbA1c reductions with favorable safety profile comparable to other GLP-1 based therapies

Association of body mass index, body fat, and weight gain with inflammation markers among rural residents in Japan

J Inflamm

And the benefits might be partly result from decrease in lectin-like oxidized receptor1 (LOX-1) followed by significant declines in cellular ROS and NF-B signaling pathways

A substrate protein and ubiquitin are covalently linked during the enzymatic reaction process known as ubiquitination