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Combination with conventional care: Maintain proper immobilization, weight-bearing restrictions, nutrition optimization (calcium, vitamin D, protein), and physical therapy as prescribed

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Figure 1 2 Role of amyloid- accumulation and neuroinflammation Amyloid-beta (A) is a peptide generated through the sequential enzymatic cleavage by -, -, and -secretases of amyloid precursor protein (APP), a transmembrane protein predominantly expressed in neurons

Hormone therapy, particularly when used for anti-aging purposes, can carry risks such as increased incidence of certain cancers, cardiovascular disease, and other health issues