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This compound has been studied for its potential to support: Integrity of the gut lining Soft tissue recovery including tendons and ligaments Angiogenesis (formation of new blood vessels) Inflammation modulation While much discussion has centered on orthopedic recovery, interest is increasing in its possible role in gut-related conditions , including discomfort linked to medications or mucosal lining damage

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MOTS-c was found to upregulate key genes in the TGF-/Smad pathway (such as TGF-1, TGF-2, and Smad7) and increase the expression of bone formation markers like alkaline phosphatase (ALP), osteocalcin, and Runx2 in bone cells

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