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The programmability and dynamics allow them to serve as precision building blocks that undergo programmed intracellular assembly and accumulate at the site of interest, thereby improving their specificity and pharmacokinetics 6,20

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CagriSema development Combination therapy trials exploring optimal dosing ratios, different target populations, and head-to-head comparisons with existing therapies

Labeled HT-29 cells were pretreated with PBS, PV2, ncAA-nanobody, PV2-PV3 fusion nanobodies and Durvalumab served as positive controls and seeded onto 12-well culture plate at 2 10 5 cells per well (macrophage tumor cell ratio: 1:4)