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In some embodiments, otic administration of the formulations or compositions described herein avoids toxicity associated with systemic administration (e.g., hepatotoxicity, cardiotoxicity, gastrointestinal side effects, and renal toxicity) of the active agents

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However, scientists discovered that EPO also has powerful tissue-protective effects

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Verschiedene Faktoren beeinflussen die Wirkung von Warfarin bei Patienten (siehe Grafik): Bislang wurden drei Gene entdeckt (GGCX, VKORC1 und CYP2C9), aber auch klinische Faktoren wie Alter, Geschlecht oder Ernhrung knnen die Wirkung beeinflussen