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Pro-Angiogenic Risk : BPC-157's ability to upregulate Vascular Endothelial Growth Factor (VEGF) raises preliminary concerns about potential support for abnormal cell growth

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Particularly important for those on acid-blocking medications, metformin, vegetarians, or patients with gastritis

For instance, a case series involving 12 women with interstitial cystitis reported symptom improvement after bladder-wall injections of BPC-157, yet the study lacked placebo controls, long-term follow-up, and was published in a non-indexed, alternative medicine journal

2016 Feb 10;1(1):e00023-15