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Credelio CAT is also indicated for treatment and control of Ixodes scapularis (blacklegged tick) infestations for one month in cats and kittens 6 months of age and older and weighing 2.0 pounds or greater

At least for metformin it can be expected that current clinical trials will catch upon this

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In addition, they found that both the transcript and the protein levels of Nrf2 and the detoxifying/antioxidant enzymes HO1 and NQO1 were significantly decreased [252]