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HuangWJZhangXChenWW.Role of oxidative stress in Alzheimers disease

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doi: 10.1172/jci152067

Cardiolipin can be oxidized by ROS or by the cardiolipincytochrome c complex ( c from cardiolipin might also be triggered by increased cytosolic calcium, which weakens the electrostatic interaction between cytochrome c and cardiolipin and further generates ROS via MPT