The factors that were historically used to indicate higher risk in the UK have no good quality clinical evidence to support their re-introduction into clinical practice
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However, in pregnancies with high blood sugar levels (such as those with GDM), the placenta's development can be affected, leading to various complications such as increased oxidative stress, fetal thrombosis, maternal vascular malperfusion, and an imbalance in vasoactive molecules
Curr Opin Biotechnol 44:94102
Because there are so many complicating factors, it's crucial to work with a healthcare provider who can evaluate your results in the context of your current symptoms and medical history and help create an effective, personalized plan