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Can supplementation with vitamin D modify thyroid autoantibodies (anti-TPO ab, anti-Tg ab) and thyroid profile (T3, T4, TSH) in Hashimotos thyroiditis

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IGF-1 LR3 has a higher binding affinity for IGF-1R and reduced IGFBP binding compared to native IGF-1, meaning free tissue exposure is greater for equivalent doses, which amplifies the theoretical risk