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doi: 10.1016/j.autrev.2025.103752 69 JiangHZhangXWuYZhangBWeiJLiJet al

Still deciding on copper peptides before or after retinol

The Phase 2 clinical data makes the case numerically

The majority of research-grade peptides clear systemically within 57 half-lives, but downstream signaling effects and extracellular matrix binding may extend biological activity beyond serum detection limits