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Some studies suggest that increasing glutathione can help overcome addictive behaviors, which span from eating disorders to alcohol/drug abuse [57, 58, 59]

We monitored ROS production, modifications in mitochondrial area and respiratory parameters from macrophages following sUA stimulus and observed that sUA is released in a hypoxic environment and, when the first signal of inflammasome activation is present, is able to trigger NLRP3 through the production of mitochondrial ROS

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