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Modern pharmacologic therapies (including conventional, biological, and novel potential small molecule disease-modifying anti-rheumatic drugs) remain the mainstay of RA treatment and there has been significant progress toward achieving disease remission without joint deformity

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Additionally, supplementing GlyNAC was also closely associated with the hallmarks of aging, including mitochondrial dysfunction, mitochondrial biogenesis, intercellular communication, nutrient sensing, loss of proteostasis, stem-cell exhaustion, genomic damage, cellular senescence, and telomere attrition

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The primary concern is additive nausea, as both compounds can independently cause gastrointestinal discomfort