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(137) further indicated that DKD microvascular complications are closely associated with abnormal BCAA metabolism, with high levels of L-leucine [area under the curve (AUC) = 0.834] and isoleucine (AUC = 0.932) demonstrating high diagnostic ability in distinguishing DKD from T2DM

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They can help you determine the optimal dosage for your specific needs, assess potential drug interactions, and recommend specialized intracellular testing (such as RBC magnesium or comprehensive trace element panels) to guide your protocol accurately

Bourke CD, Prendergast CT, Sanin DE, Oulton TE, Hall RJ, Mountford AP