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doi: 10.1016/j.bbadis.2021.166182 129 SrinivasSKMaYSammelMDChouDMcGrathCParrySet al

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The use of a rat model, although widely accepted for preliminary biomedical research, may not entirely replicate the complex pathophysiological processes of premature ovarian insufficiency in humans

Khoury et al., 2017)

For only GSSG quantification samples and the standard are treated with 4-vinylpyridine for an hour before performing glutathione assay and thus GSH is removed and only GSSG concentration is determined.