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If you do that, it should be guided and monitored

But I've never seen B12 ampoules available in the kind of smaller doses that would be needed to try this

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Emerging research has extended interest in AOD-9604 beyond metabolic applications

Curcumin is also anti-epileptic in the PTZ model, as proposed by Choudhary KM et al., who found that curcumin (100 and 200 mg/kg) lowered the seizure scores in a dose- and time-dependent manner in PTZ-kindled mice [92]