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5-Amino-1MQ doesn't act on appetite, it works by inhibiting NNMT, which shifts cell metabolism toward fat oxidation and muscle preservation

However, the compound became widely available for routine use in the treatment of B12 deficiency in the early 1950s (8)

In dietinduced obese mice, NNMTi treatment significantly reduced liver weight, liver volume, and hepatic triglyceride levels, alleviated hepatic steatosis and inflammatory infiltration, downregulated inflammatory factors (such as TNF and IL6) and lipogenic genes (such as FAS), and upregulated lipolytic genes (such as ATGL) in the liver

Some clients report feelings of light-headedness or an unusual feeling of pressure in their body when the dosage is too high

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