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3 Gut microbiota-derived SCFAs 3.1 The overview of intestinal flora The intestinal microbiota has a large number of 10 trillion or even 100 trillion microorganisms, including bacteria, fungi, and viruses (67, 68), and the development of high-throughput sequencing technology has revealed that the gut flora contains far more genes than the human genome, leading to the term second human genome (69)

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