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The statistical significance of all proteomics and secretome data was assessed using a two-tailed Students t-test with a permutation-based FDR and an S0 parameter of 0.1 in the Perseus software

As an essential AA, the supplementation of Met is necessary for the maintenance of protein synthesis and influences overall metabolism in various functions

In addition to serving as a channel for amino acids to enter and exit the cell, AATs also function as a probe for sensing amino acid levels and as an initiator of nutritional signals

Postsynaptic degeneration as revealed by PSD-95 reduction occurs after advanced Abeta and tau pathology in transgenic mouse models of Alzheimers disease