Under hypoxia or mitochondrial dysfunction, -KG can be converted to citrate by Isocitrate dehydrogenase (IDH 2) catalyzed carboxylation reaction, which is used for the synthesis of amino acids and fatty acids and the production of reducing agent NADPH
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Final Thoughts Copper peptides offer a unique, science-backed approach to skin rejuvenation
Regulation of copper homeostasis Copper homeostasis, namely, the dynamic balance in copper levels, is a tightly regulated process by various key molecules, including copper chaperones, transmembrane transporters, and transcriptional regulators (Chen et al., 2022, 2023)
Shi WJ, Feng LX, Wang X, Huang Y, Wei YF, Huang YY, Ma HJ, Wang W, Xiang MH, Gao LQ