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An 8-week randomized double-blind trial comparing GHK-Cu in nano-lipid carrier against Matrixyl 3000 showed 55.8% reduction in wrinkle volume versus control and 31.6% reduction versus the active comparator

Zhang M, Han W, Hu S, Xu H

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The peptide is an NNMT (Nicotinamide N-methyltransferase) inhibitor