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In the GCH1-BH4 pathway, BH4 functions as an antioxidant capable of trapping peroxidized lipid radicals, with GCH1 serving as the rate-limiting enzyme in BH4 biosynthesis

First, three hairpin-structured DNA probes H 1 , H 2 and H 3 were designed, H 1 including a disulfide bond (-S-S-), H 3 labeled with a fluorophore/quencher pair

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The various glucose-modified PIC/Ms improved brain by-products owing to their multivalent interaction with GLUT1 located on the brain capillary endothelial cells (109) siRNA loaded magnetic nanoparticles have been effectively used as delivery mechanisms for targeting microglia in AD to reduce neurodegeneration (110)

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