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BO is mostly seen in the sixth or seventh decades of life, the average being 55 years, but it can develop at an earlier age

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They follow a different pattern of endocrine function and communication

ROS are a necessary defense system to combat microbial respiratory infections (Lambeth, 2004), but oxidative stress and the excessive production of ROS by numerous cells including monocytes and macrophages, neutrophils, as well as pulmonary endothelial and epithelial cells play a major role in the development of ARDS and its complications during COVID-19 infections (Meftahi et al., 2021)

Its hydrating base also prevents dryness, keeping skin soft and comfortable throughout the day