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In some embodiments, the otic formulation or composition comprises about 0.9% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

Once the dopamine is ready, the cell stores it in tiny pockets that hold it safely until the right moment

116 Astrocytic asthenia is also manifested by the limited reactivity in the most vulnerable brain regions such as entorhinal and prefrontal cortices in which astrocytes do not mount a defence response in the presence of -amyloid depositions

The experimental procedures are shown in Fig

92 Active ATM forms dimers via disulfide bonds, particularly at Cys2991