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Its mitochondria-targeted analog, MitoQ, provides stronger protection by reducing ROS, increasing GSH, and limiting apoptosis, thereby preserving mitochondrial integrity [111,112,113]
No significant degeneration has classically been described in the cerebral cortex and in the striatum, although more recent findings gainsay the first neuropathological descriptions [8, 11, 15,16,17,18,19,20]