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[4] Glutathione Depletion and Supplementation in Medical Conditions Extensive research in various specialties has shown that many human diseases are associated with low glutathione levels

** The result depends on individual metabolism

Liang G, Yang J, Horton JD, Hammer RE, Goldstein JL, Brown MS (2002) Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c

Glutathione levels decline naturally with age and more steeply in women under chronic stress, poor sleep, alcohol, or hormonal changes [8]