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As a result, the shear stress imposed on the vasculature walls by these hemodynamic forces is perceived by endothelial cell mechanoreceptors, which facilitates increases in intracellular calcium concentrations

Because its a water-soluble vitamin, any excess that isnt used should be flushed from the body and not pose too much risk (not the case with fat-soluble vitamins like vitamin A)

HLA class-II-restricted CD8 + T cells contribute to the promiscuous immune response in dapsone-hypersensitive patients

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