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This occurs through the direct stimulation of RANKL in osteoblasts via transducers and the activation of STAT3 (activator of transcription 3)

Xing X, Zhao S, Xu T et al (2021) Advances and perspectives in organic sonosensitizers for sonodynamic therapy

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TNF-, IL-1 and IL-6 blockade and angiogenesis inhibition are also employed clinically due to their roles in the pathogenesis of RA ( Table 1

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