melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Mystery behind labial and oral

biological activity depends on the complex and formulation (PMC)

Overall, widespread annual surveillance of influenza does not reveal ADE of disease, even though cross-reactive strains and vaccine mismatches are common

For those with sensitivities, this band stimulates mitochondria, promotes collagen production, and contributes to skin health achieving aesthetic benefits without the intensity of traditional sauna heat

Hence, it has been demonstrated that silymarin has the growth inhibitory effect by cell proliferation suppression and apoptosis induction (11)

Most effects when they occur are mild and typically diminish as the body adjusts