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Hearts were minced finely in isolation buffer (300 mM sucrose, 10 mM Hepes, 2 mM EGTA, pH 7.2) at 4C, in the presence of 0.5 M type I protease (bovine pancreas) to release mitochondria from the muscle fibers, and then washed in the same buffer in the presence of 1 mg/mL BSA

10.1016/j.jmgm.2022.108239 23 GengC.WangZ

To avoid this complication, INH is routinely administered with vitamin B6

The body needs time to adapt to each dose level, and GI side effects (nausea, decreased appetite, occasional diarrhea) tend to peak within the first 1-2 weeks of a new dose and then diminish

The refined lattice parameters were found to be a = 5.8172 , b = 8.1805 , and c = 5.7833 , corresponding to a unit cell volume of 274.27 3