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Li M, Chen X, Li Q

7 Conclusion Flavonoids have demonstrated broad immunoregulatory and anti-inflammatory effects in both innate and adaptive immune cells, with evidence supporting therapeutic potential in RA, intestinal inflammatory diseases, metabolic disorders, CVD, respiratory diseases, etc

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A third problem lies in batch variation and lack of standardization: Plant extracts are compositionally complex, with unstable ratios of active components, making it difficult to establish clear doseresponse relationships