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Jane JA, Jr., Catalino MP, Laws ER, Jr

Consistently, irisin treatment attenuated sepsis-related AKI induced by cecal ligation and puncture (CLP) not only by blocking the ferroptosis signaling pathway but also by upregulating SIRT1/NRF2 axis activation [217]

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Lancet 366 , 649659 (2005)

10 Elevated BCAAs and their metabolites are key in the early progression of metabolic diseases such as T2D