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Consistent with these observations, heat map analysis results showed that EGCG-Zn downregulated the expression of multiple pro-inflammatory and pro-apoptotic genes in the MAPK pathway while upregulating multiple Rap1 pathway genes related to adherens junctions, cell migration, and tissue repair (Fig

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Triple-hormone-receptor agonist Retatrutide for obesity: Phase 2 trial (48-week study, up to 24% weight loss) American Diabetes Association (2023) ADA Press Release: Novel agent Retatrutide results in substantial weight reduction (83rd Scientific Sessions, Phase 2 data) ADA Meeting News (2023) Phase 2 trial results: benefits of Retatrutide in obesity, type 2 diabetes, NASH (83rd ADA Scientific Sessions coverage) ClinicalTrials.gov Study of Retatrutide (LY3437943) in adults with obesity (NCT04881760

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