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In the in vitro culture system of lamina propria mononuclear cells (LPMC) or peripheral blood mononuclear cells (PBMC) derived from CD patients, butyrate acts as a specific inhibitor of class I histone deacetylases (HDACI) and exhibits high responsiveness

GHK-Cu is a human tripeptide with a wide range of biological effects, including stimulation of collagen production, wound healing, and modulation of gene expression. Pickart & Margolina, Oxidative Medicine and Cellular Longevity How GHK-Cu Works Stimulates Collagen and Elastin Production GHK-Cu promotes the synthesis of collagen, elastin, and glycosaminoglycanskey components of the skins extracellular matrix

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