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Psychiatry 172 , 10681072 (2015)

Using of NTA, which forms 1: 1 complex with Cu(II) in our experimental conditions and showed slow demetallation of CuHSA, a K D value equal to 0.900 0.091 pM (50 mM Hepes, 50 mM NaCl, pH 7.4) was determined

For autoimmune applications, where the margin between helpful modulation and harmful stimulation may be narrow, getting these details right matters even more than in other contexts

Together, they work on two separate appetite-control systems at once GLP-1 and amylin which is why the combination outperforms either drug alone

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