It generates lipophilic radical trapping antioxidants (RTAs) to prevent the accumulation of lipid peroxides [43], while also indirectly regenerating another antioxidant, -tocopherol, to capture free radicals and inhibit ferroptosis [44,45,46]
Homma K, Fujisawa T, Tsuburaya N, Yamaguchi N, Kadowaki H, Takeda K et al (2013) SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency
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This triple-agonist mechanism makes it a subject of intense scientific interest, particularly in metabolic research