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Obesity is associated with several health complications, including an increased risk of co-morbidities, including type 2 diabetes, cardiovascular disease, chronic kidney disease (CKD) and metabolic dysfunction-associated steatohepatitis (MASH)

466,467 Another phase III trial (NCT03446001) aimed to further confirm the safety and efficacy of 16 mg/day monotherapy compared to placebo in participants with mild to moderate AD, with results pending disclosure

doi: 10.3390/jcm9124017 4 AgarwalAParekhN

Eur J Neurosci 2012;35:121829

This early preclinical report demonstrates proof-of-principle that NMDAR antagonists may represent a new class of antidepressants