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LRP targeting peptidesAngiopep-2 LRP, including LRP-1 and LRP-2, is a ubiquitous endocytic cell membrane receptor that binds various ligands and controls the permeability of the BBB [96, 125]

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Combined treatment with IC261 and APR-017 resulted in a remarkable reduction in cell viability and a significant increase in ROS level when compared to the control or single treatment groups (Fig

Though further large-scale studies are needed, the early evidence supporting peptides and supplements is compelling, especially when these tools are used in conjunction with evidence-based treatments such as behavioral therapy and medication-assisted treatment

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