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Pruritus, a common and distressing symptom, is managed with moisturizers, antihistamines, and other medications like cholestyramine, though many treatments have limited efficacy

While the diversity of GST quaternary structures might still grow with the release and accumulation of structural data, the majority of GSTs adopts the canonical dimeric quaternary structure

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Researchers using DEXA scans or waist circumference measurements often see disproportionate reductions in trunk fat compared to peripheral fat during this phase

This creates a situation where a Medicare patient with both type 2 diabetes and obesity might receive tirzepatide covered as Mounjaro for diabetes, with weight loss as a secondary benefit