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These findings support the hypothesis that the AMPK/mTOR autophagy pathway is involved in PTX resistance mediated by EV-derived VDAC1 protein

10.3390/nu16111728 62 LiS.YangD.ZhouX.ChenL.LiuL.LinR.et al (2024)

These findings suggest that secondary tumors may arise as a potential side effect of pharmacological ferroptosis induction, underscoring the need for long-term experiments to assess this possibility in suitable animal models

Light activity becomes possible for acute injuries

Nobiletin, functioning as a P-gp inhibitor, can suppress P-gp overexpression in lymphocytes in the AIA rat model when co-administered through a nanodelivery system, providing novel insights for refractory RA (26, 198)