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Oral high-dose B12 (1,000-2,000 g daily) may be considered as an alternative for patients with dietary deficiency without malabsorption who prefer this route or cannot tolerate injections

Men with asthenozoospermia may benefit more from mitochondrial-targeted antioxidants like Coenzyme Q 10 or carnitine, which improve energy metabolism [97,111]

In perimenopause, hyperactive kisspeptin neurons are now understood to drive vasomotor symptoms hot flushes and night sweats via co-expressed neurokinin B and dynorphin pathways

In reality, the treatment of underlying vector-borne infection leading to cyclical Herx flares may be the main issue

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