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NAD+ and glutathione are two essential molecules that work synergistically to power your bodys cellular repair, detoxification, and energy production systems

Glutathione Glutathione is produced exclusively in the cytosol, yet it is delivered to other cellular compartments, including the mitochondria, peroxisomes, endoplasmic reticulum, and the nucleus, as well as the extracellular space to be utilized by other tissues

ITCs are electrophilic compounds that have been shown to activate phase II detoxification enzymes, including glutathione S -transferases (GSTs), in several organisms 24,25,26

Combining them addresses liver inflammation through complementary mechanisms improved insulin sensitivity (tirzepatide) and reduced oxidative damage (glutathione)

Cells Tissues Organs 194 (1), 2537