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Since the database had a few missing values (due to missing lab or behavioral data), the regression analyses were conducted in two slightly different ways which generally yielded very similar results: 1) eliminate all participants with missing data for any of the variables in the model at the beginning of the analysis, and 2) eliminate participants on an as-needed basis (i.e., only where there is missing data for any variable in the current step in the analysis)

Ann Bauer, a co-author of the review, publicly expressed distress over how it was cited in the HHS announcement

The one exception where very gentle physical exfoliation might be considered is in rosacea patients with significant textural irregularity from phymatous changes (thickened skin)

Data statistics Data were represented as the mean standard of at least two independent experiments performed in duplicate or triplicate