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Funding This work was supported by the 2020 Basic Medical Research Fund of the Japanese Dermatological Association (donated by Shiseido) (YY)
Administration of lipoic acid (200 to 1,800 mg/day for 2 weeks to 1 year), alone or together with other nutrients, was found to lower fasting blood glucose and insulin concentrations, insulin resistance, and blood HbA1c concentration a marker of glycemic control over the past few months (60)
Summary Cellular senescence, marked by irreversible cell cycle arrest and the secretion of proinflammatory factors, contributes to aging and cancer recurrence
In general, the oral route has the lowest bioavailability of any route of administration