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Retatrutide is a triple GLP-1/GIP/glucagon receptor agonist under clinical investigation

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Side Effects and the Copper Uglies Explained GHK-Cu has a strong safety profile in topical research, but a small subset of users experience a transient phase known as the copper uglies. A 2023 clinical safety review covering 12 studies and 512 participants reported that the most common side effects of topical GHK-Cu were transient and mild

I can trace my symptoms back over 40 years though as you say - they did rather snow ball in the last few years

Unlike other B12 types, it binds well to blood proteins, allowing it to stay active for several days to weeks after administration