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Molecular engineering and activity improvement of acetylcholinesterase inhibitors: insights from 3D-QSAR, docking, and molecular dynamics simulation studies

Nevertheless, as the phenotypes caused by most yeast prions result from loss-of-function of a protein, which already performs a distinct molecular role in its native state, the functional character of the yeast prions has been contested and an alternative view presents them as analogous to human amyloidosis and other prion diseases (Wickner et al., 2011)

In 2022, Lu et al

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