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When you're working with potent, research-grade compounds, every microgram matters

The best-powered of these are still under 100 participants, rarely blinded, and typically sponsored by the manufacturer of the test cream

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Iodine, in the form of iodide, concentrates in the thyroid gland and any other tissue with the right sodium iodine symporter (NIS) protein to bring it in NIS concentrates iodide not only in the thyroid, but also in the cervix, the ovaries, placenta, eyes, skin, and lactating breast [1]