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Similarly, treatment with withaferin A, a steroidal lactone significantly increased expression of HO-1 in HUVECs and EA.hy926 endothelial cells by enhancing nuclear translocation of Nrf2

Nature 523 , 617620 (2015)

Fish, Diets and Sampling In order to avoid the metabolic disturbance of estrogen during the sexual maturation of female fish, only male zebrafish (0.25 0.03 g) were bought from Chinese National Zebrafish Resource Center (Wuhan, China)

Chronic treatments with a 5-HT(4) receptor agonist decrease amyloid pathology in the entorhinal cortex and learning and memory deficits in the 5xFAD mouse model of Alzheimers disease